1,3-Azabicyclo[3.3.0]octane

1,3-Azabicyclo[3.3.0]octane - Names and Identifiers

Name	octahydrocyclopenta[c]pyrrole
Synonyms	Gliclazide Impurity 13 3-Azabicyclo[3.3.0]octane 1,3-Azabicyclo[3.3.0]octane Octahydrocyclopenta(c)pyrrole octahydrocyclopenta[c]pyrrole Cyclopenta[c]pyrrole,octahydro- octahydrocyclopenta[c]pyrrole HCL Cis-Octahydro-cyclopenta(c)pyrrole N-Amino-3-azabicyclo[3.3.0]hydrochloride 1,2,3,3a,4,5,6,6a-octahydrocyclopenta[c]pyrrole
CAS	5661-03-0
EINECS	227-114-5
InChI	InChI=1/C7H13N/c1-2-6-4-8-5-7(6)3-1/h6-8H,1-5H2

1,3-Azabicyclo[3.3.0]octane - Physico-chemical Properties

Molecular Formula	C7H13N
Molar Mass	111.18
Density	0.934±0.06 g/cm3(Predicted)
Boling Point	165.0±8.0 °C(Predicted)
Flash Point	44.8°C
Water Solubility	1000g/L at 20℃
Vapor Presure	8.1hPa at 20℃
pKa	11.53±0.20(Predicted)
Storage Condition	2-8°C(protect from light)
Refractive Index	1.478

1,3-Azabicyclo[3.3.0]octane - Introduction

octahydrocyclopenta[c]pyrrole, also known as octahydrocyclopenta[c]pyrrole, is an organic compound. Its chemical formula is C9H15N, and its structure has a five-membered ring and an imidazole ring. The following is a description of the properties, uses, preparation and safety information of the compound:

Nature:
-Appearance: octahydrocyclopenta[c]pyrrole is a colorless to pale yellow liquid.
-Solubility: It is soluble in many organic solvents, such as ethanol, dimethylformamide and dichloromethane.
-Stability: The compound is relatively stable under conventional conditions, but may decompose under high temperature, high pressure or light.

Use:
-Chemical synthesis: octahydrocyclopenta[c]pyrrole can be used as intermediates in organic synthesis reactions and can be used to synthesize some biologically active compounds.
-Drug research: It also has certain applications in the field of drug research, and can be used as a ligand or building block of certain drugs.

Preparation Method:
octahydrocyclopenta[c] There are many preparation methods of pyrrole, and one of the more commonly used methods is synthesis by cyclization reaction of imidazole ring. Specific steps are as follows:
1. Taking benzaldehyde and ethyl acetate as raw materials, Michael addition reaction was carried out in an appropriate solvent to generate N-phenylmethacrylamide.
2. The imidazole ring is synthesized under basic conditions to obtain the octahydrocyclopenta[c]pyrrole.

Safety Information:
-When handling or storing octahydrocyclopenta[c]pyrrole, take care to avoid contact with skin, eyes and respiratory tract to prevent irritation and injury.
-When using this compound, follow laboratory safety procedures and wear appropriate protective equipment such as gloves, glasses and laboratory coats.
-If contact or aspiration occurs, immediately flush the affected area with clean water and seek medical help.
-This information only provides basic safety guidance. Please consult the relevant laboratory and chemical safety information before the experiment, and follow the correct safety operation.

Last Update：2024-04-09 15:17:58